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Hip and knee research

Safety and Effectiveness of Utilizing Virtual Reality for Total Knee Arthroplasty (TKA) for the Reduction of Acute Postoperative Pain and Opioid Use 

PI, Michael Suk, MD

This randomized controlled study will study the effects of a virtual reality-based pain management program in helping to reduce acute postoperative pain and opioid use after orthopaedic total knee arthroplasty (TKA) surgery. After surgery, participants wear a pair of goggles to create the sensation of being transported into immersive, 3D worlds. The goal is to limit the patients’ processing of pain signals, thereby reducing pain and associated opioid use.

Periprosthetic Joint Infection Causative Organisms and Their Infecting and Antibiotic Susceptibility Patterns

PI, David Maish, MD

The aim of this study is to establish infection patterns in patients who were diagnosed with periprosthetic joint infections after arthroplasty, and to identify antimicrobial susceptibility and the evolution of resistance that may have occurred over time from 2008 to 2020 in a rural health system.

The Impact of Robotic-Assisted Technology on Knee Arthroplasty Healthcare Costs and Utilization

PI, David Kolessar, MD

Robotic-assisted knee arthroplasty (rKA) has been associated with improved clinical, radiographic and patient-reported outcomes. The aim of this study is to evaluate healthcare utilization and costs associated with manual knee arthroplasty (mKA) versus rKA. This study also examines the influence of rKA technology on surgeons’ practice patterns.

An Overview of Indications, Complications, and Outcomes Following Girdlestone Arthroplasty in the Year 2020: A Retrospective Review

PI, James Murphy, MD

Resection (Girdlestone) hip arthroplasty (GRA) has historically been used as a treatment for severe, unreconstructable hip disease; however, this procedure is rarely used in modern times. This study reviews the indications and results of a large series of GRA in the current arthroplasty environment with specific attention to chronic antibiotic usage.

Diagnostic Accuracy of the New Definition of Periprosthetic Joint Infection Versus 2014 Musculoskeletal Infection Society (MSIS) Criteria

PI, David Maish, MD

Periprosthetic joint infection (PJI) is a serious complication following total joint arthroplasty. The new 2018 scoring system for diagnosing PJI demonstrated a higher sensitivity and specificity than 2014 Musculoskeletal Infection Society (MSIS) criteria. The purpose of this study is to compare the accuracy of the 2018 criteria to the 2014 MSIS criteria for the diagnosis of periprosthetic hip/knee joint infection.  

Genotype and Phenotype Associations of Developmental Dysplasia of the Hip

PI, Steven Lietman, MD

Developmental dysplasia of the hip (DDH) describes a wide spectrum of disorders ranging from minor acetabular dysplasia to irreducible dislocation of the hip. Modern medicine is still lacking a solid foundation to guide DDH screening and describe potential genetic predispositions. Early detection of DDH may help prevent further disability and improve the psychological health and quality of life of these children. The aim of our study is to establish a genetic etiology for this condition.

Can the Lateral Approach to Knee Replacement Surgery Decrease Infrapatellar Saphenous Nerve Damage and Improve Kneeling and Squatting Function?

PI, Steven Lietman, MD

Lateral approach to knee replacement may lead to lower risk of nerve damage to the anterior knee and better kneeling and squatting function than the standard medial parapatellar approach. This study will compare 12-month postoperative kneeling and squatting function between patients who had the medial parapatellar approach with anterolateral skin incision and patients who have undergone surgery using a lateral approach with anterolateral skin incision.

Aseptic Loosening in a Novel Total Knee Arthroplasty System

PI, David Kolessar, MD

Several studies have described good short-term outcomes using a novel total knee arthroplasty (TKA) implant system. However, there have been reports of early failures with aseptic loosening of the tibial component, specifically at the implant-cement interface. The purpose of this study is to describe the causes and rates of revision in patients who underwent TKA surgery with this novel system and identify factors associated with aseptic loosening.

Triathlon Titanium Knee Outcomes Study: A Prospective, Post-market, Multicenter Study of the Outcomes of the Triathlon Titanium Knee System

PI, Thomas Bowen, MD

The Triathlon Knee System, a predecessor to the Triathlon Tritanium Knee System, is designed to provide patients with more natural motion and the potential for greater implant longevity. The primary objective of this prospective, non-randomized, post-market, multicenter study is to evaluate the success rate of cementless primary total knee replacement with the Triathlon Tritanium Tibial Baseplate and Triathlon Tritanium Patella.

SWIFT Trial: Surgical Weight Loss to Improve Functional Status Trajectories following Total Knee Arthroplasty

PI, Christopher Still, DO

The purpose of this study is to determine whether weight-loss surgery prior to total knee replacement surgery reduces risk and improves long-term orthopaedic outcomes including knee range of motion, knee pain, and physical function.

Secur-Fit Advanced Outcomes: A Prospective, Post-market, Multicenter Evaluation of the Clinical Outcomes of the Secur-Fit Advanced Hip Stem

PI, Thomas Bowen, MD

The purpose of this prospective, post-market study is to evaluate and determine the success rate of the Secur-Fit Advanced Hip Stem and compare it with those reported for other primary hip stems in the scientific literature.

Michael Suk

"We are a dynamic orthopaedic translational research center… Our affiliation with various groups prove that Geisinger is a major contributor to orthopaedic research."