Agnes Sundaresan, MD
Research InterestsMy primary research interest is chronic disease epidemiology using the longitudinal electronic medical record (EMR). I focus on the environmental and genetic epidemiology of chronic respiratory inflammatory diseases and pediatric familial hypercholesterolemia, to understand the etiology and pathogenesis of these diseases. I have worked on phenotyping diseases like chronic rhinosinusitis and different asthma outcomes of interest using EMR, providing subsequent ability to study the epidemiology of these diseases at the primary care level or in the general population. I also use survey methodology to complement and evaluate EMR data for chronic rhinosinusitis. I am part of the Environmental Health Institute at Geisinger, exploring the environmental determinants of chronic rhinosinusitis and asthma, like community socioeconomic deprivation, residential greenness index, distance to roadways and community type. I am also working on evaluating different aspects of missing heritability for asthma by assessing rare variants and gene-environment interaction.
- Sundaresan AS, Hirsch AG, Young AJ, Pollak J, Tan BK, Schleimer RP, Kern RC, Kennedy TL, Greene JS, Stewart WF, Bandeen-Roche K, Schwartz BS. Longitudinal Evaluation of Chronic Rhinosinusitis Symptoms in a Population-based Sample. The journal of allergy and clinical immunology In practice. 2017. Epub 2017/11/15. doi: 10.1016/j.jaip.2017.10.012. PubMed PMID: 29133225.
- Almoguera B, Vazquez L, Mentch F, Connolly J, Pacheco JA, Sundaresan AS, Peissig PL, Linneman JG, McCarty CA, Crosslin D, Carrell DS, Lingren T, Namjou-Khales B, Harley JB, Larson E, Jarvik GP, Brilliant M, Williams MS, Kullo IJ, Hysinger EB, Sleiman PM, Hakonarson H. Identification of Four Novel Loci in Asthma in European and African American Populations. Am J Respir Crit Care Med. 2016 Sep 9. [Epub ahead of print] PubMed PMID: 2761148
- Hirsch AG, Stewart WF, Sundaresan AS, Young AJ, Kennedy TL, Greene JS, Feng W, Tan BK, Schleimer RP, Kern RC, Lidder A, Schwartz BS. Nasal and Sinus Symptoms and Chronic Rhinosinusitis in a Population-Based Sample. Allergy. 2016 Sep 3. doi: 10.1111/all.13042. [Epub ahead of print] PubMed PMID: 27590749
- Sundaresan AS, Hirsch AG, Storm M, Tan BK, Kennedy TL, Greene JS, Kern RC, Schwartz BS. Occupational and environmental risk factors for chronic rhinosinusitis: a systematic review. Int Forum Allergy Rhinol. 2015 Jun 16. doi: 10.1002/alr.21573. [Epub ahead of print] PubMed PMID: 26077513
EducationMBBS, Christian Medical College, Vellore, India, 1998-2004
Internal Medicine-Pediatric residency, Geisinger, 2008-2012
MPH, Johns Hopkins Bloomberg School of Public Health, 2011-2014