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Research Investigator I

Center for Health Research
100 North Academy Avenue
Danville, PA 17822 
Phone: 570-214-5184
Fax: 570-214-5170

Xiaowei (Sherry) Yan, PhD

Research Interests

My primary research interests lie in developing novel statistical approaches in cancer biology and carcinogenetic pathways, causal inference, as well as comparative effectiveness research (CER) based on Electronic Health Records (EHR). Specific topics of current interest are: 1) Stochastic Model of Carcinogenesis: Identify major pathways involved in cancer initiation, progression, and estimating functional relationships of genes and related pathways; 2) Causal Inference: Develop targeted estimators of target parameters within the context of realistic set-up and causal structure, especially aiming to estimate causal and non-causal parameters of interest based on observational longitudinal studies (using EHRs), with informative censoring and missingness, and 3) Comparative Effectiveness Research: Identify major confounders and missingness arising from observational studies, together with causal structure, develop estimating schemes, and applying the estimation strategy to health records to provide solid evidence to patients, clinicians and decision-makers, leading to improved health outcomes.

Recent Publications

  • Bloom F, Yan X, Graf TR, Anderer T, Davis D, Pierdon S, Pitcavage J, Stewart WF, Steele G. (2013). Primary Care Diabetes Bundle Management: Three-Year Outcomes for Macro-vascular and Micro-vascular Events. AJMC , in press.  
  • Minassian VA, Yan X, Lichtenfeld MJ, Sun H, Stewart WF. (2012, Apr). Predictors of Care Seeking in Women with Urinary Incontinence. Neurourology and Urodynamics , 31(4), 470-474. Full Text
  • Minassian VA, Yan X, Lichtenfeld MJ, Sun H, Stewart WF. (2012, Aug). The Iceberg of Urinary Incontinence in Women: From the Population to the Specialist. International Urogynecology Journal , 23(8), 1087-1093. Full Text
  • Hayden RT, Yan X, Wick MT, Rodriguez AB, Xiong X, Ginocchio CC, Mitchell MJ, Caliendo AM, College of American Pathologists Microbiology Resource Committee. (2012, Feb). Factors Contributing to Variability of Quantitative Viral PCR Results in Proficiency Testing Samples: A Multivariate Analysis. Journal of Clinical Microbiology , 50(2), 337-345. Full Text
  • Tan WY, Yan XW. (2010, April). A New Stochastic and State Space Model of Human Colon Cancer Incorporating Multiple Pathways. Biology Direct Theramic Series: Evolution and Cancer , 5, 26. Full Text


MS, Chinese Academy of Sciences & University of Science and Technology of China, 1998-2001
MS, University of Wisconsin-Madison, 2002-2005
PhD, University of Memphis/St. Jude Children's Research Hospital, 2006-2010