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Youngjin Cho, PhD

Associate Professor of Immunology
Department of Medical Education
Research & Scholarship
North Campus

LOCATION(S)
Geisinger Commonwealth School of Medicine
Medical Sciences Building
525 Pine St.
Office 3082W, Lab 3064W
Scranton, PA 18509
570-687-9717
Fax: 570-504-9639
ycho3@geisinger.edu

Youngjin Cho, MS, PhD

Research interests

Youngjin Cho, MS, PhD, is associate professor of immunology in the Department of Medical Education. She received her bachelor of science and master of science degrees from the Korean Advanced Institute of Science and Technology, South Korea, and her PhD in pathobiology at Keck School of Medicine at University of Southern California in affiliation with Children Hospital of Los Angeles. She worked as a postdoctoral fellow at Children Hospital of Los Angeles, Marry Babb Randolph Cancer Center at West Virginia University and Geisinger Commonwealth School of Medicine.

With the growth of Geisinger Commonwealth, Dr. Cho transitioned from a biomedical researcher, conducting a research related to breast cancer and mesenchymal stem cells utilizing mouse model, to a medical educator. She has been co-directing medical science courses for pre-clerkship students and overseeing the immunology content delivery throughout the curriculum. She completed an International Association of Medical Science Educator (IAMSE) fellowship. Since 2019, she has been the immunology lead on the editorial board of Aquifer Science™, an organization to develop and disseminate teaching and learning tools that promote cognitive integration and collaborative teaching of basic and clinical sciences in health profession education.

Dr. Cho's educational research focuses on effective instructional approaches in medical education. She was funded to develop a curriculum to enhance medical student training toward people with intellectual disabilities and has led several funded educational research projects.

Recent publications

  • Cho Y, Gutierrez L, Bordonaro M, Russo D, Hooven J, et al. Effects of propolis and gamma-cyclodextrin on intestinal neoplasia in normal weight and obese mice. Cancer medicine. 2016
  • Cho Y, Silverstein R, Geisinger MT, Martinkovich S, Corkill H, Cunnick JM, Planey SL, Arnott JA. AFAP1 Is a Novel Downstream Mediator of TGF-β1 for CCN2 Induction in Osteoblasts. PLoS One. 2015 Sep 4;10(9)
  • Cunnick J, Kim S, Hadsell J, Cerra C, Reiser P, Flynn D, Cho Y (2014) Actin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary gland. Oncogene 34:2640-9
  • Snyder BN*, Cho Y*, Qian Y, Coad JE, Flynn DC, Cunnick JM. (2011) AFAP1L1 is a novel adaptor protein of the AFAP family that interacts with cortactin and localizes to invadosomes. Eur J Cell Biol 90:376-89
  • Clump AC, Yu JJ, Cho Y, Gao R, Jett J, Zot H, Cunnick JM, Snyder B, Clump AC, Dodrill M, Gannett P, Coad JE, Shurina R, Figg WD, Reed E, and Flynn DC. (2010) A polymorphic variant of AFAP-110 enhances cSrc activity. Transl Oncol 3:276-285.
  • Cunnick JM, Schmidhuber S, Chen G, Yu M, Yi SJ, Cho YJ, Kaartinen V, Minoo P, Warburton D, Groffen J, Heisterkamp N. (2009) Bcr and Abr cooperate in negatively regulating acute inflammatory responses. Mol Cell Biol 29:5742-5750.
  • Dorfleutner A, Cho YJ., Vincent D, Cunnick J, Lin H, Weed S, Stehlik C, and Flynn DC. (2008) Phosphorylation of AFAP-110 affects podosome lifespan in A7r5 cells. Journal of Cell Science 121:2394-2405.
  • Flynn DC, Cho YJ, Vincent D, and Cunnick J. (2008) Podosomes and invadopodia: Related structures with common protein components that may promote breast cancer cellular invasion. Breast Cancer: Basic and clinical research 1: 1-13.
  • Kweon SM, Cho YJ, Minoo P, Groffen J, Heisterkamp N. (2008) Activity of the Bcr GTPase-activating domain is regulated through direct protein/protein interaction with the Rho guanine nucleotide dissociation inhibitor. J Biol Chem 283:3023-30.
  • Cho YJ*, Cunnick J*, Kaartinen V, Groffen J, Heisterkamp N. (2007) Abr and Bcr, two   homologous RacGAPs, control multiple cellular functions of murine macrophages. Mol Cell Biol. 27:899-911.
  • Cunnick J, Kaur P, Cho YJ, Groffen J, Heisterkamp N. (2006) Use of bone marrow-derived macrophages to model murine innate immune responses. J Immunol Methods. 1-2:96-105.
  • Cho YJ*, Hemmeryckx B*, Groffen J, Heisterkamp N. (2005) Interaction of Bcr/Abl with C3G, an exchange factor for the small GTPase Rap1 through the adapter protein Crkl. Biochem Biophys Res Commun. 4:1276-83.
  • Cho YJ*, Zhang B*, Kaartinen V, Haataja L, de Curtis I, Groffen J, Heisterkamp N. (2005) Generation of rac3 null mutant mice: role of Rac3 in Bcr/Abl-caused lymphoblastic leukemia. Mol Cell Biol. 13:5777-85.

Education

Bachelor's – Korea Advanced Institute of Science and Technology (KAIST), Daejon, South Korea
MS – KAIST, Deajon, South Korea
PhD – Keck School of Medicine, University of Southern California, Los Angeles, CA

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