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College of
Health Sciences

Scott A. LeMaire, MD
Professor of Cardiothoracic Surgery
Associate Chief Scientific Officer 
Associate Dean for Research
100 N Academy Ave.
MC 44-00 
Danville, PA 17822-4400

Scott A. LeMaire, MD

Research Interests

My primary area of interest is thoracic aortic aneurysm and dissection, with a particular emphasis on organ protection during aortic surgery, outcomes of aortic operations, genetic aspects of thoracic aortic disease, and molecular mechanisms of aortic wall degeneration.

Recent Publications

Current research projects/collaborators

Improving our understanding of heritable thoracic aortic disease; Cellular and molecular drivers of acute aortic dissections; Prediction of aortic dissection and rupture in Marfan syndrome using nano-radiomics; Endothelial dysfunction in the development of aortic degeneration, dissection, and rupture; Pro-inflammatory pyroptotic cell death in aortic degeneration; Does Ciprofloxacin increase the susceptibility to arterial aneurysm and rupture in vascular Ehlers-Danlos Syndrome?


Quincy College, Quincy, Illinois, B.S. in Biology, Minors in Chemistry and English, June 1988 
Northwestern University Medical School, Chicago, Illinois, M.D., June 1992 
Baylor College of Medicine, Houston, Texas, Residency in General Surgery, 1992-1997, Residency in Cardiothoracic Surgery, 1997-1999, Clinical Scientist Training Program Certificate of Added Qualification, May 2006

Recent grants

NIH/NHLBI R01-HL159988; NIH/NHLBI R01-HL158157; Leducq Foundation for Cardiovascular Research International Networks of Excellence Program (22CVD03)

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